By William T. Blows
Written by means of an skilled nurse lecturer who additionally educated as a psychological well-being nurse, this book explores the underlying biology linked to the pathology of psychological future health problems and the similar worried process. Integrating comparable pharmacological and genetic wisdom, The organic foundation of Nursing: psychological overall healthiness covers themes together with: the body structure of neurotransmission and receptors the traditional human mind hormones and psychological healthiness the biology of feelings, rigidity, nervousness and phobic states the biology of substance abuse developmental problems genetics and psychological well-being affective disorders: depression and suicide schizophrenia the growing older mind and dementia degenerative ailments of the mind epilepsy and sleep problems. correct to nurses in any respect levels in their education, this is often an important textual content for psychological healthiness nursing scholars, practitioners and educators.
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Extra resources for The Biological Basis of Nursing: Mental Health
Example text
The activated Gs protein moves along the inner membrane, and collides with and activates adenylyl cyclase (AC). This in turn binds adenosine triphosphate (ATP) to form cyclic adenosine monphosphate (cAMP). cAMP is free to move into the cell (it is a second messenger) and activate protein kinase A (PKA), which can have a multitude of different effects on the cell. 3. g. a sodium channel, allowing ions to pass through the membrane. 10). 10). 2). They do not directly influence ionic channels but do cause changes in the metabolism of the postsynaptic cell.
This causes the opening of a chloride (Cl−) channel and chloride enters the postsynaptic membrane. The entry of this negative ion causes the resting potential to become even more negative, preventing any chance of an action potential in that membrane. (b) An excitatory receptor binding glutamate. This causes the opening of a sodium channel and sodium ions (Na+) to enter. The entry of a positive ion sets up an action potential in the postsynaptic membrane. See page 35 respond. After binding, the neurotransmitters will be removed from the receptor.
E. they pass right through the membrane, appearing on both sides). Cells can of course produce proteins, so they can also produce receptors when necessary. This means that cells can upregulate their receptors by producing more of them, increasing the receptor density of their membrane and therefore binding more of the neurotransmitter. This is likely to be the consequence of reduced quantities of available neurotransmitter. Alternatively, cells can downregulate their membrane receptor density by slowing receptor production, especially if the neurotransmitter is in 42 NEUROTRANSMITTERS AND RECEPTORS abundance.