By Elka Touitou, Brian W. Barry
Enhancement in Drug Delivery
I learn this e-book with nice curiosity and located that it comprises very invaluable details. using enhancers is frequently crucial within the layout of novel pharmaceutical items and new cures. i believe that this ebook provides a concise, readable, and in-depth evaluation of the basics, purposes, and optimizations of some of the capability to advertise drug absorption for the main used management routes. The booklet comprises a variety of examples of particular supply platforms in addition to equipment in their evaluate either in vitro and in vivo. The reader is electrified with new rules to decide on the ideal enhancer for a brand new product and is supplied with "pro" and "contra" in regards to the use of particular permeation enhancement techniques.
The individuals are renowned foreign specialists from academia and undefined.
In end, this quantity presents a multidisciplinary and entire reference that could be successfully utilized by researchers within the pharmaceutical and academia in addition to a textbook for pharmacy scholars at a number of levels.Enhancement in Drug supply
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J. J. Louisos, and A. Antonopoulos. 1972. Aminopeptidasische eigenschaften der mundschleimhaut beim menschen (Properties of aminopeptidase of human buccal mucosa). Enzymologia 43:143. 127. R. Robinson. 1992. Drug delivery via the mucous membranes of the oral cavity. J Pharm Sci 81:1. 128. , et al. 1993. Wheater’s functional histology, a text and colour atlas, 3rd ed. Edinburgh: Churchill Livingstone. 129. , et al. 1970. Drug absorption III: Effect of membrane storage on the kinetics of drug absorption.
I. 2001. Design and power of a population pharmacokinetic study. Pharm Res 18:75. N. S. Bertino, Jr. 2004. Genetic polymorphisms of cytochrome P450 enzymes and the effect on interindividual, pharmacokinetic variability in extensive metabolizers. J Clin Pharmacol 44:447. , L. Z. Benet. 1996. Active secretion and enterocytic drug metabolism barriers to drug absorption. Adv Drug Deliv Rev 20:99. , et al. 2000. Progress in predicting human ADME parameters in silico. J Pharmacol Toxicol Methods 44:251.
Ito, S. 1969. Structure and function of the glycocalyx. Fed Proc 28:12. 96. B. Millar. 1981. Intestinal diffusion barrier: Unstirred water layer or membrane surface mucous coat? Science 214:1241. 97. , N. Aoyagi, and T. Terao. 1995. Estimation of agitation intensity in the GI tract in humans and dogs based on in vitro=in vivo correlation. Pharm Res 12:237. 98. , H. Goig, and U. Muller. 1987. Closed rat jejunum segment in situ: Role of pre-epithelial diffusion resistance (unstirred layer) in absorption process and model analysis.