By The International Agency for Research on Cancer
Conventional natural medications surround an exceptionally diversified workforce of arrangements that originate from many various cultures. in recent times, such items became broadly on hand commercially in constructed nations, the place combos ready from medicinal vegetation were advertised or makes use of that have been by no means pondered within the conventional therapeutic platforms from which they emerged.
In many nations, natural medicinal drugs will not be topic to rigorous criteria with appreciate to production, efficacy, caliber and safeguard. for instance, natural treatments containing plant species of the genus Aristolochia and utilized in Europe for bodyweight loss have triggered kidney disorder and urothelial cancers and at the moment are labeled as carcinogenic to people.
This monograph evaluates the carcinogenic hazards to people posed via a few conventional natural medications, Fumonisin B1, and the commercial natural chemical compounds naphthalene and styrene, and offers an replace of the knowledge at the carcinogenicity of aflatoxins. An Annex to the amount describes fungal assets and formation of aflatoxins in meals and feeds, and discusses useful suggestions for relief of aflatoxin degrees.
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Additional resources for Some Traditional Herbal Medicines, Some Mycotoxins, Naphthalene and Styrene
Example text
Bull. , Haroun, L. & Vainio, H. (1987) Appendix 1. Activity profiles for genetic and related tests. In: IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Suppl. 6, Genetic and Related Effects: An Updating of Selected IARC Monographs from Volumes 1 to 42, Lyon, IARCPress, pp. , Partensky, C. & Vainio, H. (1986) Response of experimental animals to human carcinogens: an analysis based upon the IARC Monographs Programme. Carcinogenesis, 7, 1853–1863 GENERAL REMARKS ON THE SUBSTANCES CONSIDERED This volume of the IARC Monographs considers some traditional herbal medicines, including extracts from certain plants of the genera Aristolochia, Rubia, Morinda and Senecio; some mycotoxins, specifically aflatoxins and fumonisin B1; and two industrial chemicals, naphthalene and styrene.
About 5000 traditional remedies are available in China; they account for approximately one fifth of the entire Chinese pharmaceutical market (Li, 2000). 2 Japanese traditional medicine Many herbal remedies found their way from China into the Japanese systems of traditional healing. Herbs native to Japan were classified in the first pharmacopoeia of Japanese traditional medicine in the ninth century (Saito, 2000). 3 Indian traditional medicine Ayurveda is a medical system primarily practised in India that has been known for nearly 5000 years.
These bioassays, as well as numerous studies on the toxicity and mechanisms of action of fumonisin B1 are reviewed and evaluated in the present volume. GENERAL REMARKS ON THE SUBSTANCES CONSIDERED 37 Naphthalene and styrene Naphthalene was originally planned for inclusion in IARC Monographs Volume 77, Some Industrial Chemicals (2000), but was withdrawn from consideration at that time because the Monographs programme became aware of new carcinogenicity studies of this compound that were nearing completion.