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This precise reference presents the 1st systematic assurance on hand in a single-source quantity at the program of fabrics technology thoughts to the pharmaceutical field-offering a finished application for the actual characterization of uncooked fabrics, drug ingredients, and formulated items.
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J Control Release 2:257–275 11. Edgar WM (1992) Saliva: its secretion, composition, and functions. Br Dent J 172(8):305– 112 12. Mattes RD (1997) Physiologic responses to sensory stimulation by food: nutritional implications. J Am Diet Assoc 97(4):406–413 13. Rathbone MJ, Ponchel G, Ghazali FA (1996) Systemic oral mucosal drug delivery and delivery systems. In: Rathbone MJ (ed) Oral mucosal drug delivery. Marcel Dekker, New York 14. Rathbone MJ, Drummond BK, Tucker IG (1994) The oral cavity as a site for systemic drug delivery.
When the tablets are placed in the buccal cavity, they form a gel from which the prochlorperazine is released and absorbed. The plasma levels achieved at steady state on a dosage regimen of one buccal tablet twice daily are similar to those observed with the standard oral dosage of one 5 mg tablet taken three times daily. Its formulation contains compressible sugar, Povidone K30, xanthan gum, locust bean gum, talc, magnesium stearate and riboflavin sodium phosphate. Buccolam This oral mucosal solution, containing 10 mg midazolam in 2 mL, is for paediatric use [35].
Buccolam This oral mucosal solution, containing 10 mg midazolam in 2 mL, is for paediatric use [35]. Buccolam (ViroPharma SPRL) is provided in a prefilled, age-specific dose formulation for administration to an area between the cheek and gum. 7. Its formulation contains sodium chloride, water for injections, hydrochloric acid for pH adjust- 2 Overview of Oral Mucosal Delivery 25 ment and conversion of midazolam to the hydrochloride salt and sodium hydroxide (again for pH adjustment). Epistatus This liquid buccal formulation of midazolam is available for the treatment of status epilepticus and serious tonic–clonic seizures in community settings.