By Xiang Yang Liu, James J. De Yoreo
We all have examine the significant capability inherent in nanotechnology and the fascinating effect it has had in altering our way of life within the twenty first century. one of many simple concerns confronting us is how one can fabricate units or fabrics at the nano scale. what's the simple physics governing the formation of nano levels? How can organic structures encourage us to formulate nano scale architectures, within the approach nature has regularly performed and keeps to do? those are major components of concentration during this e-book. the purpose of this reference is to take us to the basis of those matters: the solid-fluid interfacial constructions and the fundamental interactions among structural devices that make certain the kinetics of nano debris and meeting formation, and thus the ensuing constructions and functionalities of the nano stages and units. through taking a clean examine the unconventional nano constitution engineering and floor probing applied sciences from a world perspective of basic rules, the 2 volumes of this publication direct our concentration from the macroscopic part to the nano buildings starting from inorganic to bio nano fabrics. that includes contributions from a few overseas specialists within the similar fields, this e-book deals a finished and synergistic investigate those tough matters by way of theoretical modeling, desktop simulations, complicated floor probing and fabrication and interface characterizations. The e-book additionally presents a hyperlink to the nanostructure engineering of a few novel fabrics taking part in a major position in advancing applied sciences during this box. quantity I specializes in either the theoretical and experimental elements of crystal surfaces and solid-fluid interfacial buildings, the impression of ordering and disordering of the interfacial molecules at the kinetics of crystalline topic, and specifically at the nano crystalline section and the formation of self-organized nanofiber networks. Expertly written chapters extend the present wisdom on surface/interfacial buildings linked to bulk levels to the micro/nano structural area, offering examples of the characterization and manipulation of self-organized nano buildings. the subject material covers additionally the rules and applied sciences bearing on nano stages, surface/interface constitution formation and characterization, and fabrication. quantity II is dedicated to the meeting of bio-related nano constructions and hybrid nano fabrics and platforms. The half on bio-related nanostructures specializes in the aggregation and trend formation of protein molecules, or biomaterials within the bulk and at the floor of specified substrates. the right way to regulate the method of biomineralization, organic matrices, hierarchical constructions and different bio-related fabrics by means of hoping on powerful tools, comparable to templating, AFM, Chemoselective Ligation, scanning probe nanolithography can also be handled intimately. moreover, leading edge suggestions to engineer advanced nano buildings reminiscent of molecular layout and molecular self meeting are highlighted.
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Extra info for Nanoscale Structure and Assembly at Solid-Fluid Interfaces: Volume I: Interfacial Structures versus Dynamics, Volume II: Assembly in Hybrid and Biological ... (Nanostructure Science and Technology)
Sample text
The phosphate group of phosphocitrate is in perfect register with the phosphate groups of the surface. All negatively charged groups of phosphocitrate are participating in binding to the (101) surface of struvite. slightly less negatively charged than PC. Also, acetohydroxamic acid seemed incapable of significantly affecting struvite growth, although the crystals did appear less bulky and more plate-like, elongating along the [100] direction and sometimes forming characteristic X-shape crystals.
Summary All these results strongly suggest that the PC inhibition of ATP-induced CPPD crystal formation in both articular cartilage vesicles and cartilage explants [77] could occur via stereospecific and irreversible binding of phosphocitrate to (010) and (011) faces of CPPD, which in turn leads to the retardation of crystal growth in the direction perpendicular to these faces and eventually cessation of crystal growth. Binding of PC, although of a lesser strength, may also occur on (100), (01–1), (001) and (1–10) faces which also show nonnegligible binding energies, nearly equal to each other.
G. metalloproteinase synthesis and mitogenesis [82], and of inhibiting further BCP and CPPD crystal formation in articular tissue [77]. 6. 1. Introduction Hydroxyapatite is one of the most important minerals in the human body. It constitutes almost the entire mineral phase of bones and tooth enamel. Its ubiquity however, sometimes may lead to cases of unwanted biomineralization that results in many pathological conditions. Recently, it has been shown in vitro that the growth of hydroxyapatite crystals can be efficiently controlled using phosphocitrate, a naturally occurring compound.