By Arun Kumar, Heidi M. Mansour, Adam Friedman, Eric R. Blough

There is a transparent desire for leading edge applied sciences to enhance the supply of healing and diagnostic brokers within the physique. contemporary breakthroughs in nanomedicine at the moment are making it attainable to carry medicinal drugs and healing proteins to neighborhood components of illness or tumors to maximise medical gain whereas restricting uncomfortable side effects. Nanomedicine in Drug supply gives an summary of features of nanomedicine to assist readers layout and increase novel drug supply platforms and units that construct on nanoscale technologies.

Featuring contributions via top researchers from world wide, the e-book examines:

  • The integration of nanoparticles with healing agents
  • The synthesis and characterization of nanoencapsulated drug particles
  • Targeted pulmonary nanomedicine supply utilizing inhalation aerosols
  • The use of organic systems―bacteria, cells, viruses, and virus-like particles―as companies to convey nanoparticles
  • Nanodermatology and the position of nanotechnology within the analysis and remedy of epidermis disease
  • Nanoparticles for the supply of small molecules, comparable to for gene and vaccine delivery
  • The use of nanotechnologies to modulate and adjust wound healing
  • Nanoparticles in bioimaging, together with magnetic resonance, computed tomography, and molecular imaging
  • Nanoparticles to augment the potency of present anticancer drugs
  • The improvement of nanoparticle formulations
  • Nanoparticles for ocular drug delivery
  • Nanoparticle toxicity, together with routes of publicity and mechanisms of toxicity
  • The use of animal and mobile types in nanoparticles safeguard reviews

With its functional specialize in the layout, synthesis, and alertness of nanomedicine in drug supply, this booklet is a priceless source for medical researchers and someone operating to take on the demanding situations of offering medicines in a extra particular and effective demeanour. It explores quite a lot of promising ways for the analysis and therapy of illnesses utilizing state of the art nanotechnologies.

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Extra resources for Nanomedicine in drug delivery

Sample text

Pharmacokinetics and biodistribution of nanoparticles. Mol. Pharmaceut. 5:496–504. -M. et al. 2009. Biomedical nanoparticle carriers with combined thermal and magnetic responses. Nano Today 4:52–65. , Welsher, K. et al. 2009. Carbon nanotubes in biology and medicine: In vitro and in vivo detection, imaging and drug delivery. Nano Res. 2:85–120. M. 2009. Liposomes and nanoparticles: Nanosized vehicles for drug delivery in cancer. Trends Pharmacol. Sci. 30:592–599. H. M. 2004. Challenges and solutions for the delivery of biotech drugs—A review of drug nanocrystal technology and lipid nanoparticles.

Applications of nanoparticles in biology. Adv. Mater. 20:4225–4241. Duncan, R. and Gaspar, R. 2011. Nanomedicine(s) under the microscope. Mol. Pharmaceut. 8:2101–2141. H. and Wipf, P. 2009. Nanoparticles in cellular drug delivery. Bioorg. Med. Chem. 17:2950–2962. Foldvari, M. and Bagonluri, M. 2008. Carbon nanotubes as functional excipients for nanomedicines: II. Drug delivery and biocompatibility issues. Nanomedicine 4:183–200. , Shahiwala, A. et al. 2008. A review of stimuli-responsive nanocarriers for drug and gene delivery.

Et al. 2009. Carbon nanotubes in biology and medicine: In vitro and in vivo detection, imaging and drug delivery. Nano Res. 2:85–120. M. 2009. Liposomes and nanoparticles: Nanosized vehicles for drug delivery in cancer. Trends Pharmacol. Sci. 30:592–599. H. M. 2004. Challenges and solutions for the delivery of biotech drugs—A review of drug nanocrystal technology and lipid nanoparticles. J. Biotechnol. 113:151–170. , and Gohla, S. 2000. Solid Lipid nanoparticles (SLN) for controlled drug delivery: A review of the state of the art.

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