By J. Mandel, L. F. Nanni
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189 - 0. 050 = 0. 139, and 0. 326 - 0. 050 == 0. 276. e. 1 to 2. Acand example in the columns labeled Inspection of , in a ratio tually, 0. 139 is slightly larger than (0. 276/2). of We will assume that this is due TABLE 4. 8. STUDY OF ACCURACY OF GLUCOSE DETERMINATION Serum sample Reference value Grand average (R) (1) 40. 76. 4 204. 89 76. 136. 25 y== " === y= . TABLE 4. 9. 156 214. 4652 6030 I. 7059 6425 6425 0516 + 0. 0027571 x . = 0. 0019 x = concentration of d = glucose, in mg/dl absorbance fitted value residual solely to experimental error in the measured absorbance values, thus assuming that any errors in the concentration values are negligibly -small.
2-5 In the is 3. , for DF = 142 (DF= number of degrees of freedom). a value of3. e. , for equal efficacy of the two drugs) is less than 0. 0002. The smallness of this probability is of course a strong indication that the hypothesis of equal efficacy of the two drugs is unacceptable. It is then generally concluded that the experiment has demonstrated the superior efficacy of E as compared to S. For example, the conclusion might take the form that " the odds favoring the effectiveness of E over S are better than M to I" where is a large number (greater than 100 in the present case).
276/2). of We will assume that this is due TABLE 4. 8. STUDY OF ACCURACY OF GLUCOSE DETERMINATION Serum sample Reference value Grand average (R) (1) 40. 76. 4 204. 89 76. 136. 25 y== " === y= . TABLE 4. 9. 156 214. 4652 6030 I. 7059 6425 6425 0516 + 0. 0027571 x . = 0. 0019 x = concentration of d = glucose, in mg/dl absorbance fitted value residual solely to experimental error in the measured absorbance values, thus assuming that any errors in the concentration values are negligibly -small. general model If a represents the true value of the " blank" and 13 the absorbance per unit concentration , we have, according to Beer s law: E(y) .