By C. Mills, H. Wichers, K Hoffmann-sommergruber
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105. HERRMANN D, HENZGEN M, FRANK E, RUDESCHKO O, JÄGER L. Effect of hyposensitization for tree pollinosis on associated apple allergy. J Invest Allergol Clin Immunol, 1995, 5(5): 259–67. 106. KELSO J M, JONES R T, TELLEZ R, YUNGINGER J W. Oral allergy syndrome successfully treated with pollen immunotherapy. Ann Allergy Asthma Immunol, 1995, 74(5): 391–6. 107. ASERO R. Effects of birch pollen specific immunotherapy on apple allergy in birch pollen hypersensitive patients. Clin Exp Allergy, 1998, 28(11): 1368–73.
They may have information about food alerts (foods found to contain unlabelled allergens) or lists of currently ‘safe’ foods. The support of such groups should help allergic individuals to handle their food allergy safely and confidently, with less impact on their daily activities. 83 With the implementation of the new European Directive on food labelling (2003/89/EC), label reading and identification of food allergens will be easier for allergic consumers within the European Union. 2 (which includes the most important allergenic foods) have to be declared in the labels, independently of the quantity in which they are present in the food (the 25% rule has been abolished) and with a clear reference to the specific name used in the list.
116 Furthermore, mapping of IgE binding epitopes might provide prognostic information as for instance demonstrated in milk allergic children. 118 Microarray immunoassays might be also used to assess epitope binding. Recently, this approach has been validated in peanut allergy. Epitope binding for 213 overlapping 20-residue peptides of the major peanut allergens has been investigated. 5 New forms of immunotherapy for food allergy Based on extensive characterisation of food allergens, and on a better understanding of the immunological mechanisms involved in allergic diseases, new immunotherapeutic modalities for food allergy are under development.