By Skoner
Appearing a radical and specific examine of 1 of the most typical but much less adequately understood explanations of human sickness, this all-inclusive reference examines the epidemiology, pathophysiology, and destiny therapies for bronchial asthma and respiration infections. This advisor additionally comprises up to date effects from medical trials of antiviral brokers that discover new avenues of therapy-including interferons, ICAM-1 receptor blockades, vaccines, and mediator antagonists.
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Additional resources for Lung Biology in Health & Disease Volume 154 Asthma and Respiratory Infections
Example text
One of thcse is the increased numbers of small children i n whom ARIs are a larger problem. 2% of deaths occurred there (39). The annual causes of the deaths of children under 5 are shown in Table 5 (40). 22 29 l 100 nt 16 Denny Pneumonia -A- I I I Tuberculosis 6% Measles 17% Pertussis 7% Figure 8 Percentage distribution of ARI-related deaths of children under 5. (Adapted from Ref. ) accounted for over one-half of all deaths. The percentage distribution of the ARIrelated deaths of children under 5 is shownin Figure 8 (39).
Pneumonia, responsible for 70% of the ALIU-related deaths, is clearly the big problem in children in the developing world. Further examplesof the problems presentedby ARIs in these children are shown in the next three tables (13). The proportionof children presenting with ARIs in outpatient services varied from 30 to 60% (Table 6). 3% (Table 8). The agents causing ARIs are the same all over the world, wherever studies have been done. Thus, RSV, the parainfluenza viruses, the adenoviruses. 3 Ref.
RevInfectDis 1991; 3(suppl 6):S454-S462. Sclwyn BJ, on behalf of the Coordinated Data Group o f BOSTID Researchers. The epitlcmiology of acute respiratory tract infections i n young children: comparison of findings from several dcveloplng countrlcs. Rev Infect Dis 1990: 12(suppl 8):S870- S888. 38. McIntosh K. JInfectDis 1990; 12(suppl 8):867-S869. 39. Grant JP. {. Ncw York: Oxford University Press, 19Y3. Grant JP. cw, IYYO. NewYork:OxfordUniversity Press, 1990. 41. Denny FW. Clyde W A Jr. Acute respiratory tract Infections: an overview.