By Thomas W. Sadler
Delivering unprecedented complete colour diagrams and scientific photos, Langman's clinical Embryology, 13e is helping clinical, nursing, and healthiness professions scholars boost a uncomplicated knowing of embryology and its scientific relevance. Concise bankruptcy summaries, appealing scientific correlates packing containers, scientific difficulties, and a transparent, concise writing variety make the subject material obtainable to scholars and appropriate to instructors.
The new version is more advantageous by means of over a hundred new and up-to-date illustrations, extra scientific pictures and images of early embryologic improvement, and an improved bankruptcy at the cardiovascular process. additionally, on-line instructing and studying assets contain the absolutely searchable textual content on-line, in addition to an interactive Quiz financial institution for college students and a picture bank.
* scientific Correlates containers illustrated through instances and photographs conceal delivery defects, developmental abnormalities, and different scientific phenomena.
* greater than four hundred illustrations—including full-color line drawings, scanning electron micrographs, and medical images—clarify key features of embryonic development.
* simple genetic molecular biology rules are highlighted during the textual content to hyperlink embryology to different severe specialties.
* bankruptcy assessment figures offer a visually compelling advent to every chapter.
* difficulties to unravel (with targeted solutions behind the publication) assist you check your understanding.
* An increased thesaurus defines key words and concepts.
* a web interactive USMLE-style query financial institution is helping you overview for checks and get ready for the forums.
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Additional info for Langman's Medical Embryology (13th Edition)
Example text
Oocyte im m ediately after ovulation, showing the spindie of the second m eiotic división. B. A spermatozoon has penetrated the oocyte, which has finished its second m eiotic división. Chromosomes of the oocyte are arranged in a vesicular nucleus, the female pronucleus. Heads of several sperm are stuck in the zona pellucida. C. Male and female pronuclei. D,E. Chromosomes become arranged on the spindie, spiit longitudinally, and move to opposite poles. F. Two-cell stage. FERTILIZATION Fertilization, the process by which male and female gametes fuse, occurs in the ampuUary región o f the uterine tube.
Thinning o f the cervical mucus occurs to allow passage o f sperm. ■ The anterior lobe o f the pituitary gland is stimulated to secrete LH. At midcycle, there is an LH surge that: ■ Flevates concentrations o f maturationpromoting factor, causing oocytes to com plete meiosis I and initiate meiosis II ■ Stimulates production o f progesterone by follicular stromal cells (luteinization) ■ Causes follicular rupture and ovulation Ovulation In the days immediately preceding ovulation, under the influence o f FSH and LH, the vesicu lar follicle grows rapidly to a diameter o f 25 mm to becom e a mature vesicular (graafian) fol licle.
During the last few days of m aturation of vesicular follicles, estrogens, produced by follicular and thecal cells, stim ulate increased production of LH by the pituitary gland [Fig. 1], and this hormone causes the follicle to enter the m ature vesicular [graafian) stage, to complete meiosis I, and to enter meiosis II, where it is arrested in metaphase approxim ately 3 hours before ovulation. and floats out o f the ovary (Fig. 3). Some o f the cumulus oophorus cells then rearrange themselves around the zona pellucida to form the corona radiata (Figs.