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In general, higher concentrations of acetone resulted in death sooner than lower Health Effects 51 concentrations. That very high concentrations of acetone are required to cause death of animals is reinforced by the fact that no deaths were reported for rats exposed to acetone at 4,210 for 8 hours to 126-129 ppm for 25 minutes or mice exposed to <84,194 ppm for 8 hours. No studies were located regarding death of animals after intermediate- or chronic-duration inhalation exposure to acetone. Systemic Effects The systemic effects of inhalation exposure to acetone in humans and animals are discussed below.

If you are exposed to acetone, many factors determine if you’ll be harmed and how badly. These factors include the dose (how much), the duration (how long), and how you’re exposed. You must also consider the other chemicals you’re exposed to and Public Health Statement for Acetone 41 your age, sex, nutritional status, family traits, lifestyle, and state of health. WHAT IS ACETONE? Acetone is a chemical that is found naturally in the environment and is also produced by industries. Low levels of acetone are normally present in the body from the breakdown of fat; the body can use it in normal processes that make sugar and fat.

Your body normally contains some acetone because it’s made during the breakdown of fat. Your body will make more acetone from body fat if you are on a low-fat diet. In addition to the acetone that your body makes from normal processes, acetone can enter your body if you breathe air that contains acetone, drink water or eat food that contains acetone, or if you touch liquid acetone or soil that contains acetone. The bloodstream absorbs acetone rapidly and completely from the lungs and stomach. The bloodstream can also absorb acetone from the skin, but less rapidly than from the lungs and stomach.