By Arthur M. Silverstein
Written through an immunologist, this publication strains the concept that of immunity from precedent days as much as the current day, reading how altering ideas and applied sciences have affected the process the technology. It exhibits how the personalities of scientists or even political and social elements motivated either concept and perform within the box. With interesting tales of clinical disputes and transferring medical tendencies, each one bankruptcy examines a huge part of this self-discipline that has been so primary to the advance of recent biomedicine. With its biographical dictionary of vital scientists and its lists of important discoveries and books, this quantity will give you the such a lot whole ancient reference within the box.
. Written in a sublime type by way of long-time training immunologist
. Discusses the altering theories and applied sciences that guided the field
. Tells of the intriguing disputes between favorite scientists
. Lists all of the vital discoveries and books within the field
. Explains intimately the numerous Nobel prize-winning contributions of immunologists
Read or Download A History of Immunology (2nd Edition) PDF
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Extra info for A History of Immunology (2nd Edition)
Example text
Lectures on the Comparative Pathology of Inflammation, London, Keegan, Paul, Trench, Tru¨bner, 1893; reprinted by Dover, New York, 1968. 48. , J. Prakt. , May, 1879, cited by Sirotinin, Z. Hyg. 4:262, 1888. 49. , C. R. Acad. Sci. 89:498, 1880; 90:1526, 1880; 91:148, 1880. 50. , Infection and Resistance, New York, Macmillan, 1914. 51. , Bull. Hist. Med. 48:1, 1974. , Species and Specificity: An Interpretation of the History of Immunology, Cambridge, Cambridge University Press, 1995. 52. , Centralbl.
The osmotic theory was advanced by the prominent pathologist Baumgarten,53 and was based on the suggestion that bacteria were destroyed in the body by osmotic rupture of their membranes. Again, it was supposed that bacterial growth resulted in the production of an increasingly less favorable osmotic environment which would presumably persist even after the initial infection had been cleared. Baumgarten maintained this view for many years and through many editions of his Textbook of Pathogenic Microorganisms, and held that the only function of antibodies was to render bacteria more susceptible to osmotic shock.
13 British workers were in general neutral on the issue, with the notable exception of the Francophile Lord Lister, who repeatedly acknowledged the debt that his antiseptic theories owed to Pasteur and Metchnikoff. However, the principal division in the cellularist–humoralist battle was between France and Germany – a division that reflected the overall nationalistic tendencies of the time. England had for over 600 years been the traditional enemy of France, dating from the time that the descendants of the Norman conquerors of England laid claim to their old lands and even to the throne of 2 Cellular vs humoral immunity 31 France.