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The biggest impact that 3D PET has had is on the detector and electronics performance. Random coincidences increase as the square of the singles rates on the detectors and therefore 3D performance is maximal at the lowest counting rates practical. In neurological "activation" studies using either H2l50 or l50-butanol the total dose that could be delivered in anyone injection had to be drastically reduced [10,11,12,13]. This can be exploited by allowing the same total dose of radiotracer to be delivered over a greater number of scans, with less dose being injected in each scan.
6. Production cost estimates. The following estimates are to be seen as guidelines only. 3 M$ The cost range for the building indicated above is meant to reflect all from modifications of an existing building to a new building. Cost variations of cyclotronlhot lab depend on si;ze of cyclotron, number of tracers/precursors purchased and number of hot cells and instruments for the hot lab. Finally, the choice of PET scanner will to a large extent depend on whether the in-house program is primarily clinical or research oriented.
The biggest impact that 3D PET has had is on the detector and electronics performance. Random coincidences increase as the square of the singles rates on the detectors and therefore 3D performance is maximal at the lowest counting rates practical. In neurological "activation" studies using either H2l50 or l50-butanol the total dose that could be delivered in anyone injection had to be drastically reduced [10,11,12,13]. This can be exploited by allowing the same total dose of radiotracer to be delivered over a greater number of scans, with less dose being injected in each scan.