By Martin M. Zdanowicz
Proposing the entire details your scholars want in an available structure, necessities of Pathophysiology for Pharmacy will supply scholars a pragmatic figuring out of the pathophysiologic foundation of chosen ailments whereas supplying a reason for next drug remedy.
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Extra resources for Essentials of pathophysiology for pharmacy: An Integrated Approach
Example text
4). Drug-induced aplastic anemia is usually a dose-dependent phenomenon. The clinical manifestations of aplastic anemia will depend on the extent to which hematopoiesis is impaired. General symptoms of anemia such as pallor, fatigue and lethargy can occur initially. Bleeding in the skin and from the nose, mouth and body orifices may also occur from a lack of platelet production by the abnormal bone marrow. Increased susceptibility to infection is also seen as a result of diminished white blood cell production.
Lymphoma — Malignant tumor of lymphatic tissue. Glioma — Malignant tumor of the glial support cells in the central nervous system. Metastasis — The ability of tumor cells to spread to other parts of the body and establish secondary tumors. Malignant tumor cells can break off and utilize blood vessels or lymphatic vessels to spread to other areas of the body. Tumor cells enhance their potential for metastatic spread by releasing protease enzymes that digest the extracellular matrix surrounding adjacent cells.
What are some common sites of metastasis for tumors? • Define oncogenesis. Discuss some of the theories of how it might occur. List some viruses that are oncogenic, as well as the cancers they may cause. • What is a carcinogen? List some substances that are carcinogenic. • List the local and systemic effects of cancer. • Define cancer cachexia. Why might it occur? ” • What are tumor cell markers? How are they used clinically? • Discuss the various treatment options for cancer. Include the drawbacks of each.