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In 1859 he and E. Noeggerath wrote a textbook for midwives and on children’s and women’s diseases. Jacobi wrote on a large number of pediatric problems: the throat (1859), diet for children (1872), diphtheria (1876), intestinal illness (1887), the thymus gland (1889), and infant and child care (1896–1902). Jacobi also contributed three monographs to Gerhard’s Handbuch, manual on hygiene in childbirth (1876), diphtheria (1877), and dysentery (1877). He also published important works on the history of pediatrics.

Jacob’s works are (1) a commentary on the forms of the letters of the alphabet written in Provence around 1270 (Madda’ei ha-Yahadut, 2 (1927), 201–12); (2) a commentary on Sefer *Yeẓ irah now lost, though the first part may have been preserved in a Florence manuscript (Plut. II, Ms. 53, pp. 33–42). , Florence II, 412), parts of which were published by G. Scholem in Kitvei Yad be-Kabbalah biYrushalayim (1930), 208–13. Jacob’s authorship is attested by his pupil Moses of Burgos who cites a number of passages in his master’s name.

Jacob was apparently one of the teachers of Jacob *Tam. According to the tosafists, Jacob was the author of a work entitled Seder Olam, a chronology of the tannaim and amoraim similar to that found in the anonymous commentary to Pirkei Avot, in the Maḥ zor *Vitry. Until recently Jacob was regarded as the author of this commentary, but it has now been established that it is not his, though it contains extracts from his commentary on Avot, as well as a number of verses with the acrostic of his name.

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