By Hans Schreier

Demonstrates how substitution of a number of ligands can render albumin a flexible focusing on instrument for selective drug accumulation in a number of mobilephone populations of the liver! This booklet discusses actual, chemical, and organic techniques to drug focusing on know-how, concentrating on oral, dispersed method, topical, dermal, transdermal, and inhalation supply, and the improvement of unique formulations which are matched by way of cutting edge equipment layout. Considers the efforts in biotechnology and molecular biology to provide clever drug supply units through exploiting organic pathways! Containing over 1100 references to facilitate extra examine, Drug focusing on know-how В·

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Extra resources for Drug Targeting Technology: Physical, Chemical and Biological Methods (Drugs and the Pharmaceutical Sciences)

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5 and higher, Chem Pharm Bull 45:1350–1353 (1997). 24. A. G. Eshra, Der Einfluß von sauer oder basisch reagierenden Modellsubstanzen auf die Stabilita¨t von Filmumhu¨llungen beim Wechsel von organischen auf wa¨ßrige Herstellungsmethoden, Dissertation, Freiburg 1982. 25. T. Waaler, S. A. Sande, B. W. Mu¨ller, G. Schu¨ller-Lisether, The influence of thermal neutron irradiation on the in vitro characteristics of ASA oral dosage forms—Validation of neutron activation, Eur J Pharm Biopharm 43:159–164 (1997).


Illum, S. S. Davis, W. Haresign, J. Jabbal-Gill, and M. Hinchcliffe, Use of a Pig Model for Colon Specific Delivery of Peptides, Proteins and Other Drugs, European Symposium on Formulation of Poorly-Available Drugs for Oral Administration, Editions de Sante´, Paris, 1996, pp. 183–186. 45. W. Rubas, J. Villagran, M. Cromwell, A. McLeod, J. Wassenberg, and R. P. Pharma Sciences 5:93–97 (1995). 46. D. R. Friend, Oral Colon-specific Drug Delivery, CRC Press, Boca Raton, Ann Arbor, London, Tokyo, 1992.

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