By Anya M Hillery, Kinam Park

This booklet presents a accomplished creation to complex drug supply and concentrating on, overlaying their rules, present purposes, and power destiny advancements. This version has been up to date to mirror major developments and state of the art advances that experience happened because the first variation was once released. all of the unique chapters were retained, however the fabric therein has been up to date. 8 new chapters were additional that care for totally new applied sciences and approaches.

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Extra resources for Drug Delivery: Fundamentals and Applications

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Kreuter 2007; Danhier et al. 2012; Sealy 2014). Gold NPs have also been used to bind and deliver drugs. Natural polymeric NCs include proteins, such as albumin, which has been used to bind and deliver paclitaxel in the Abraxane®NP formulation (Celgene). NPs made from hemoglobin, collagen, and casein have also been extensively studied. ” Important advances in the field were carried out by George and Catherine Wu (Wu and Wu 1987) who used poly(l-lysine) to complex DNA and form a polyplex, which they targeted to hepatocytes by conjugating a hepato-specific asialoglycoprotein to the carrier.

Hiait. 1951. Cellulose acetate phthalate as an enteric coating material. J Am Pharm Assoc 40(10):520–525. Matsumura, Y. and H. Maeda. 1986. A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanism of tumoritropic accumulation of proteins and the antitumor agent SMANCS. Cancer Res 46:6387–6392. Nishiyama, N. and K. Kataoka. 2006. Current state, achievements, and future prospects of polymeric micelles as nanocarriers for drug and gene delivery. Pharmacol Ther 112:630–648. Okada, H.

A. Peppas. 2006. Design of poly(ethylene glycol)-tethered copolymers as novel mucoadhesive drug delivery systems. Eur J Pharm Biopharm 63:11–18. S. Hoffman, N. Murthy et al. 2000. Molecular engineering of proteins and polymers for targeting and intracellular delivery of therapeutics. J Control Release 65:203–220. , G. Kopia, and S. Hayashi, et al. 2001. Stent-based delivery of sirolimus reduces neointimal formation in a porcine coronary model. Circulation 104(10):1188–1193. F. F. van Nostrum et al.

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