By Joint Formulary Committee

The British nationwide Formulary (BNF) is your crucial reference booklet for prescribing, dishing out, and administering drugs.

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Ask if the patient is already taking other drugs including self-medication drugs, health supplements, complementary and alternative therapies; interactions may occur; . age and hepatic or renal disease may alter the metabolism or excretion of drugs, so that much smaller doses may be needed. Genetic factors may also be responsible for variations in metabolism, notably of isoniazid and the tricyclic antidepressants; . prescribe as few drugs as possible and give very clear instructions to the elderly or any patient likely to misunderstand complicated instructions; .

G. transient increase in liver enzymes). Side-effects are generally listed in order of frequency and arranged broadly by body systems. Occasionally a rare side-effect might be listed first if it is considered to be particularly important because of its seriousness. g. cancers, chloroquine retinopathy, and retroperitoneal fibrosis) may become manifest months or years after exposure. Any suspicion of such an association should be reported directly to the MHRA through the Yellow Card Scheme. The elderly Particular vigilance is required to identify adverse reactions in the elderly.

Outside office hours a telephone-answering machine will take messages. uk The MHRA’s database facilitates the monitoring of adverse drug reactions. uk. uk/drugsafetyupdate. Self-reporting Patients and their carers can also report suspected adverse drug reactions to the MHRA. uk. Alternatively, patient Yellow Cards are available from pharmacies and GP surgeries. uk. Prescription-event monitoring In addition to the MHRA’s Yellow Card Scheme, an independent scheme monitors the safety of new medicines using a different approach.

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