By Anthony J. Hickey, Timothy M. Crowder, Margaret D. Louey, Norman Orr

Exploring the expansion in wisdom of particle homes and the diversity of technological advances in particle manufacture, this booklet supplies readers the instruments they should comprehend particulate technology and its use within the undefined. The authors disguise particulate fabric, its shape and construction, sampling from our bodies of powder, particle dimension descriptors and information, habit of debris, instrumental research, particle measurement dimension and synergy of followed recommendations, actual habit of a powder, and in vitro and in vivo functionality standards. They draw the parts of particulate technological know-how right into a unmarried concise description in their integration within the context of product improvement.

Show description

Read or Download A Guide to Pharmaceutical Particulate Science PDF

Best pharmacy books

Free Energy Calculations in Rational Drug Design

Unfastened strength calculations signify the main exact computational technique on hand for predicting enzyme inhibitor binding affinities. Advances in machine strength within the Nineties enabled the sensible program of those calculations in reason drug layout. This ebook represents the 1st accomplished evaluation of this starting to be zone of study and covers the elemental conception underlying the tactic, a number of state-of-the-art recommendations designed to enhance throughput and dozen examples in which loose power calculations have been used to layout and review power drug applicants.

The School of Pharmacy, University of London. Medicines, Science and Society, 1842–2012

The varsity of Pharmacy, collage of London: drugs, technology and Society, 1842-2012 represents the wealthy heritage of the college of London institution of Pharmacy via a variety of colour photos, vital advances within the pharmacy career, cultural milestones, biographies and extra. Written in an attractive and authoritative variety, this e-book depicts the chronological background of the college from its institution in 1842 to the current day with a nod towards its aspirations for the long run.

Venom Genomics and Proteomics

This quantity presents the reader with fresh advances within the fields of molecular toxinology, the biotechnological functions of venom pollutants, and antivenom construction. The content material of the twenty chapters of Venom Genomics and Proteomics illustrates not just the large growth made because the implementation of omics applied sciences within the box of toxinology, yet one additionally realizes the line nonetheless forward to arrive a holistic view of venomous structures.

Pharmaceutical Process Scale-Up

Concentrating on clinical and sensible points of technique scale-up, this source information the idea and perform of shifting pharmaceutical tactics from laboratory scale to the pilot plant and creation scale. It covers parenteral and nonparenterel beverages and semi-solids, items derived from biotechnology, dry mixing and powder dealing with, granulation and drying, fluid mattress purposes, compaction and tableting, and movie coating and regulatory standards for scale-up and postapproval alterations.

Additional resources for A Guide to Pharmaceutical Particulate Science

Sample text

P. 1989. The Andersen impactor: calibration, wall losses and numerical simulation. J. Aerosol Sci. 20:67–90. , and N. Adhage. 2000. Freeze-dried inclusion complexes of tolfenamic acid with beta cyclodextrins. Pharm. Dev. Tech. 5:571–574. , and J. Wells. 2001. Powder mixing. Drug Dev. Ind. Pharmacy 27:599– 612. , and L. Villafuerte-Robles. 2001. Effect of carrier excipient and processing on stability of indorenate hydrochloride/excipient mixtures. Pharm. Dev. Tech. 6:551–561. Visser, J. 1989. An invited review.

Staniforth, J. , and J. E. Rees. 1982a. Effect of vibration time, frequency and acceleration on drug content uniformity. J. Pharmacy Pharmacol. 34:700–706. Staniforth, J. , and J. E. Rees. 1982b. Electrostatic charge interactions in ordered powder mixes. J. Pharmacy Pharmacol. 34:69–76. Staniforth, J. , and J. E. Rees. 1983. Segregation of vibrated powder mixes containing different concentrations of fine potassium chloride and tablet excipients. J. Pharmacy Pharmacol. 35:549–554. Staniforth, J.

3. Mixtures of D and L crystals in solution will be optically inactive but can be resolved, unlike meso-form. Crystalline racemates are normally considered to belong to one of two basic classes: • Conglomerate: an equimolal mechanical mixture of two pure enantiomorphs; • Racemic compound: an equimolal mixture of two enantiomers homogeneously distributed throughout the crystal lattice. Racemates can be resolved manually or by forming a salt or an ester with an optically active base (usually an alkaloid) or alcohol followed by fractional distillation.

Download PDF sample

Rated 5.00 of 5 – based on 34 votes