By Anthony J. Hickey, Timothy M. Crowder, Margaret D. Louey, Norman Orr
Exploring the expansion in wisdom of particle homes and the diversity of technological advances in particle manufacture, this booklet supplies readers the instruments they should comprehend particulate technology and its use within the undefined. The authors disguise particulate fabric, its shape and construction, sampling from our bodies of powder, particle dimension descriptors and information, habit of debris, instrumental research, particle measurement dimension and synergy of followed recommendations, actual habit of a powder, and in vitro and in vivo functionality standards. They draw the parts of particulate technological know-how right into a unmarried concise description in their integration within the context of product improvement.
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Additional resources for A Guide to Pharmaceutical Particulate Science
P. 1989. The Andersen impactor: calibration, wall losses and numerical simulation. J. Aerosol Sci. 20:67–90. , and N. Adhage. 2000. Freeze-dried inclusion complexes of tolfenamic acid with beta cyclodextrins. Pharm. Dev. Tech. 5:571–574. , and J. Wells. 2001. Powder mixing. Drug Dev. Ind. Pharmacy 27:599– 612. , and L. Villafuerte-Robles. 2001. Effect of carrier excipient and processing on stability of indorenate hydrochloride/excipient mixtures. Pharm. Dev. Tech. 6:551–561. Visser, J. 1989. An invited review.
Staniforth, J. , and J. E. Rees. 1982a. Effect of vibration time, frequency and acceleration on drug content uniformity. J. Pharmacy Pharmacol. 34:700–706. Staniforth, J. , and J. E. Rees. 1982b. Electrostatic charge interactions in ordered powder mixes. J. Pharmacy Pharmacol. 34:69–76. Staniforth, J. , and J. E. Rees. 1983. Segregation of vibrated powder mixes containing different concentrations of fine potassium chloride and tablet excipients. J. Pharmacy Pharmacol. 35:549–554. Staniforth, J.
3. Mixtures of D and L crystals in solution will be optically inactive but can be resolved, unlike meso-form. Crystalline racemates are normally considered to belong to one of two basic classes: • Conglomerate: an equimolal mechanical mixture of two pure enantiomorphs; • Racemic compound: an equimolal mixture of two enantiomers homogeneously distributed throughout the crystal lattice. Racemates can be resolved manually or by forming a salt or an ester with an optically active base (usually an alkaloid) or alcohol followed by fractional distillation.